Editorial Reviews
Book Description
Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via the ouabain-sensitive sodium/potassium ATPase. The sodium entry channels are the rate-limiting determinant for transport and are regulated by several different hormones. The sodium channels also play a significant role in a number of disease states, like hypertension, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity provides the first in-depth exchange of ideas concerning these sodium channels, their regulation and involvement in normal and pathophysiological situations.
Key Features
* Summarizes current state of amiloride-sensitive sodium channel field
* Analyzes structure-function of epithelial sodium channels
* Discusses immunolocalization of epithelial sodium channels
* Examines hormonal regulation of sodium channels
* Discusses sodium channels in lymphocytes, kidney, and lung
* Considers mechanosensitivity of sodium channels
* Provides ideas on sodium channels and disease
Book Info
Univ. of Alabama, Birmingham. Provides information concerning sodium channels, their regulation, and their involvement in normal and pathophysiological situations. For researchers. Softcover, hardcover not available.
--This text refers to the
Paperback
edition.
Amiloride-Sensitive Sodium Channels, Physiology and Functional Diversity (Current Topics in Membranes, Volume 47) (Current Topics in Membranes)
Amiloride-Sensitive Sodium Channels, Physiology and Functional Diversity (Current Topics in Membranes, Volume 47) (Current Topics in Membranes),Dale J. Benos,Academic Press,0121533476,Biochemistry,Life Sciences - Biochemistry,Life Sciences - Biology - Molecular Biology,Life Sciences - Biophysics,Life Sciences - Cytology,Membrane Physiology,Pathophysiology,Science,Science/Mathematics,Science / Biophysics
Books Info:
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